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Tesamorelin is mainly used to reduce stubborn deep belly fat (visceral fat) while helping preserve muscle by boosting your body’s own growth hormone.

Tesamorelin is a lab-made version of a natural hormone in your body called growth hormone-releasing hormone (GHRH). When you inject it, it signals your pituitary gland to release more of your own growth hormone in a way that closely mimics the body’s normal daily pattern. Unlike taking growth hormone itself, Tesamorelin works by boosting what your body already produces. The main reason people use it is for its strong effect on deep belly fat (visceral fat) — the kind that sits around your organs and is harder to lose with diet and exercise alone. It was originally approved to treat excess visceral fat in people with HIV-related lipodystrophy, and research showed it can meaningfully reduce that stubborn abdominal fat while generally helping preserve muscle. Many people also notice secondary benefits like improved recovery, better body composition, and sometimes clearer thinking or better sleep, though those effects vary from person to person.